https://doi.org/10.1140/epjs/s11734-025-01965-6
Regular Article
On the issue of taking into account the physical characteristics of radiation sources used in combined radiation technologies for sterilization of bone implants
1
Lomonosov Moscow State University, Moscow, Russia
2
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants, Moscow, Russia
3
Skobeltsyn Institute of Nuclear Physics, Moscow, Russia
a
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Received:
13
July
2024
Accepted:
16
September
2025
Published online:
28
September
2025
Abstract
Current work carries out a simulation of an experiment on radiation sterilization of bone implants in the GEANT4 software package. The uniformity of irradiation of cortical bone fragments was assessed and the conditions of radiation treatment were determined, under which the dose distribution in the sample is more uniform. Thus, for each value of the thickness of the irradiated sample, it is possible to select the type of irradiation, the energy of the particle beam, geometric parameters and install additional modifiers to obtain optimal processing schemes to ensure maximum uniformity of irradiation. The dependences of the type of absorbed dose distributions on the geometric parameters and characteristics of the source are investigated. Based on the obtained information, practical recommendations have been developed to optimize the parameters of the technology of radiation treatment of bone implants used at the second stage of combined sterilization methods.
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© The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature 2025
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
