https://doi.org/10.1140/epjs/s11734-026-02158-5
Review
Morphological imaging (IHC) of Lyve-1-positive structure in the human brain
1
Department of Pathological Anatomy, Saratov State Medical University Named After V.I. Razumovsky, Ministry of Health of the Russian Federation, B.Kazachya, 112, 410012, Saratov, Russia
2
Department of Biology, Saratov State University, Astrakhanskaya 82, 410012, Saratov, Russia
a
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Received:
25
December
2025
Accepted:
26
January
2026
Published online:
2
March
2026
Abstract
The study and exploration of the lymphatic system in the brain remains a highly relevant and ongoing area of research. The proposed innovative technique of double staining the lymphatic network in the brain using immunohistochemistry opens up new possibilities for a more in-depth understanding of its structure, function, and role in processes related to thanatogenesis in various diseases. In addition, it provides valuable insights into the activation of this system through photobiomodulation, which could have significant implications for research and treatment options.
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© The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature 2026
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
