https://doi.org/10.1140/epjs/s11734-026-02213-1
Regular Article
Diagnostic performance of two-dimensional echocardiography in Saudi patients with ischemic heart disease
1
Central Labs, King Khalid University, P.O. Box 960, AlQura’a, Abha, Saudi Arabia
2
Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, 61421, Abha, Saudi Arabia
3
Radiology and Medical Imaging Department, College of Applied Medical Sciences in Al-Kharj, Prince Sattam Bin Abdulaziz University, 11942, Al-Kharj, Saudi Arabia
a
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Received:
12
August
2025
Accepted:
14
February
2026
Published online:
7
March
2026
Abstract
Catheterization and computed tomography (CT) are standard methods for detecting ischemic heart disease (IHD), but their invasiveness and associated risks can compromise patient safety. Two-dimensional echocardiography (2D echo) offers a non-invasive alternative for diagnosis and prognosis of IHD. This study evaluated the diagnostic performance of 2D echo in patients with IHD. This retrospective cohort study examined clinical and imaging data from 100 Saudi patients diagnosed with IHD from January 27, 2023 to January 27, 2025. The studied dataset consisted mostly of 2D echocardiographic findings, with IHD-related echocardiographic results verified by coronary angiography, which had previously been conducted as part of routine clinical care. Significant 2D echo findings included left ventricular (LV) end-diastolic dimension > 50 mm, left ventricular ejection fraction (LVEF) ≥ 50%, aortic sclerosis, wall motion abnormalities (WMAs), mitral annular calcification, and left atrial enlargement (> 50 ml in males, > 45 ml in females) (P ≤ 0.05). 2D echo demonstrated 92% sensitivity, 33.33% specificity, and 90.29% overall diagnostic accuracy for IHD. In summary, 2D echo is a valuable, non-invasive tool for diagnosing, managing, and prognosticating IHD. The study confirms 2D echo’s high sensitivity and diagnostic accuracy while highlighting its complementarity with traditional invasive coronary angiography.
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© The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature 2026
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
