Wettability conundrum: Discrepancies of soft contact lens performance in vitro and in vivo
Clinical Research Center, School of Optometry, University of California, Berkeley, CA 94720-2020, USA
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Revised: 15 June 2011
Published online: 30 August 2011
The recognition and appreciation of soft contact lenses as simple, efficient and aesthetically gratifying vision-correction devices is ever growing, especially among younger population. Stable thin tear film uniformly spread over corrective lens surface is essential for acute vision, and also for comfortable and safe contact lens wear. The significant efforts have been invested by the contact lens industry to develop soft lens surface that is completely wet by tear aqueous in the ocular environment. Number of the publications dedicated to the wettability properties of the soft hydrogel lenses is on the steady rise. However, the clinical results show that no unambiguous correlation emerges when lens surface wettability in vitro is judged against tear film stability evaluated in vivo. This paper assesses and compares the modern techniques used for evaluation of soft contact lens surface wettability and reports some findings regarding relations between lens surface wettability in vitro and in vivo.
© EDP Sciences, Springer-Verlag, 2011