https://doi.org/10.1140/epjst/e2013-02048-1
Regular Article
Synchronization of low-frequency oscillations in the cardiovascular system: Application to medical diagnostics and treatment
1 Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia
2 Department of Nano- and Biomedical Technologies, Saratov State University, Saratov, Russia
3 Saratov Research Institute of Cardiology, Saratov, Russia
a e-mail: ponomarenkovi@gmail.com
Received: 16 July 2013
Revised: 13 August 2013
Published online: 28 October 2013
We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1 Hz. A quantitative estimation of this synchronization based on calculation of relative time of phase synchronization of oscillations is proposed. We show that assessment of synchronization between the considered oscillations can be useful for selecting an optimal dose of beta-blocker treatment in patients after acute myocardial infarction. It is found out that low value of synchronization between the low-frequency rhythms in heart rate and blood pressure at the first week after acute myocardial infarction is a sensitive marker of high risk of mortality during the subsequent 5 years.
© EDP Sciences, Springer-Verlag, 2013
