Advances in optical microscopy revolutionize the practice of surgical pathology with rapid and non-destructive tissue assessment
Translational and Advanced Bioimaging Laboratory, Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China
Accepted: 22 January 2022
Published online: 3 February 2022
Rapid and non-destructive histological imaging with minimal tissue preparation is challenging and yet appealing medical pursuit. Recent advances in optical imaging technologies enable rapid and high-resolution imaging of fresh resection tissues, showing great potential to streamline the current clinical practice in surgical margin assessment. In addition, deep-learning-assisted virtual staining holds great promise to facilitate clinical translations of these imaging methods with training-free image interpretation by pathologists. Here, we review different imaging platforms which can provide immediate on-site feedback to surgeons and pathologists for intraoperative decision-making.
© The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature 2022