https://doi.org/10.1140/epjs/s11734-022-00467-z
Review
Advances in optical microscopy revolutionize the practice of surgical pathology with rapid and non-destructive tissue assessment
Translational and Advanced Bioimaging Laboratory, Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China
Received:
28
October
2021
Accepted:
22
January
2022
Published online:
3
February
2022
Rapid and non-destructive histological imaging with minimal tissue preparation is challenging and yet appealing medical pursuit. Recent advances in optical imaging technologies enable rapid and high-resolution imaging of fresh resection tissues, showing great potential to streamline the current clinical practice in surgical margin assessment. In addition, deep-learning-assisted virtual staining holds great promise to facilitate clinical translations of these imaging methods with training-free image interpretation by pathologists. Here, we review different imaging platforms which can provide immediate on-site feedback to surgeons and pathologists for intraoperative decision-making.
Photonic Materials: From Fundamentals to Applications. Guest editors: Rajesh V. Nair, Fan Wang, Xusan Yang, Chennupati Jagadish.
© The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature 2022